By definition, clodronate liposome is a drug delivered using liposome (a synthetic lipid that encapsulates other substances for ease of administration into the body). Liposome is manly a medium which carries the highly hydrophilic Clodronate thus facilitating its transport into the target organ. Essentially, the aim of this type of drug administration is to achieve higher macrophage depletion after an intravenous injection of the drug.
The principle behind this new method of drug administration is based on the use of synthetic lipid (Liposome) as a Trojan horse. Once ingested, the lipid is digested by the macrophages thus releasing Clodronate. This if followed by the release of the active components such as bisphosphonates which are good inhibitors of many autoimmune conditions.
Examples of the disease this drug is expected to treat include metastatic carcinomas of the breast, multiple myeloma and osteoporosis. It is also expected to be the best solution for autoimmune hyemolitic anemia, cancers and tumors in general. Significant strides have also been made with the drug during tests as far as inhibition of macrophages activities in therapies such gene and transplantation. Even in the handling of neurological disorders, this drug will be the best.
Since other bisphosphonates are in the market, it is easy to predict the side effects that may be associated with the drug once it is released. There is no need to worry though as these effects are classified as mild. For example, a few patients do report stomach pains, nausea and vomiting. In some rare scenarios, bisphosphonates may have some serious reactions.
Apart from loss of appetite, the other complications include heavy breathing, hives and skin rashes. Though some of these may not need one to see a doctor, the cases of difficulty in breathing certainly does require the attention of one. You should therefore not hesitate to report to your physician for help if the side effects take longer than normal.
Clodronate products may also lead to swelling, mouth pain and malaise. As mentioned before, you need the attention of a physician. Since the drug is not in the market currently, you do not need to judge it by these pre-release precautionary measures. It is possible that the drug will turn out just fine.
Some general contraindications are common with most prescription drugs. For instance, you should not take the drug if you are allergic to Clodronates or bisphosphonates. Similarly, expecting or breastfeeding mothers should not use the drug. Patients with kidney problems or using other bisphosphonate drugs should not use the drug too. It is also advisable that you stay from these types of drugs if you have inflammation of the gastro intestines.
Clodronate liposome as mentioned before is a prescription drug and thus cannot be shared with a family member, even if they have the same conditions. On the other hand, one cannot use the drugs unless the doctor prescribes it. Once it is officially released, it is expected to bring the much-needed cure for cancer. However, success will depend on how strict the patients will follow the prescription of the doctor.
The principle behind this new method of drug administration is based on the use of synthetic lipid (Liposome) as a Trojan horse. Once ingested, the lipid is digested by the macrophages thus releasing Clodronate. This if followed by the release of the active components such as bisphosphonates which are good inhibitors of many autoimmune conditions.
Examples of the disease this drug is expected to treat include metastatic carcinomas of the breast, multiple myeloma and osteoporosis. It is also expected to be the best solution for autoimmune hyemolitic anemia, cancers and tumors in general. Significant strides have also been made with the drug during tests as far as inhibition of macrophages activities in therapies such gene and transplantation. Even in the handling of neurological disorders, this drug will be the best.
Since other bisphosphonates are in the market, it is easy to predict the side effects that may be associated with the drug once it is released. There is no need to worry though as these effects are classified as mild. For example, a few patients do report stomach pains, nausea and vomiting. In some rare scenarios, bisphosphonates may have some serious reactions.
Apart from loss of appetite, the other complications include heavy breathing, hives and skin rashes. Though some of these may not need one to see a doctor, the cases of difficulty in breathing certainly does require the attention of one. You should therefore not hesitate to report to your physician for help if the side effects take longer than normal.
Clodronate products may also lead to swelling, mouth pain and malaise. As mentioned before, you need the attention of a physician. Since the drug is not in the market currently, you do not need to judge it by these pre-release precautionary measures. It is possible that the drug will turn out just fine.
Some general contraindications are common with most prescription drugs. For instance, you should not take the drug if you are allergic to Clodronates or bisphosphonates. Similarly, expecting or breastfeeding mothers should not use the drug. Patients with kidney problems or using other bisphosphonate drugs should not use the drug too. It is also advisable that you stay from these types of drugs if you have inflammation of the gastro intestines.
Clodronate liposome as mentioned before is a prescription drug and thus cannot be shared with a family member, even if they have the same conditions. On the other hand, one cannot use the drugs unless the doctor prescribes it. Once it is officially released, it is expected to bring the much-needed cure for cancer. However, success will depend on how strict the patients will follow the prescription of the doctor.
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